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Whitepaper
Murine NASH model could provide insights into NASH development and progression
Researchers explore a multidisciplinary approach to addressing current NAFLD and NASH challenges.
Technical Note
Expanding imaging multiplexing capabilities with PhenoVue Fluor 400LS - Phalloidin
This technical note offers tips and best practices relating to fluorescent signal quality using PhenoVue Fluor 400LS Phalloidin stain.
Application Note
Phenotype discrimination using the PhenoVue cell painting and multi-organelle staining kits
In this study, we analyzed the phenotypes induced by a set of 15 reference compounds using both the PhenoVue cell painting kit and the PhenoVue multi-organelle staining kit to compare phenotypic discrimination results of the two assays.
Article
Busting high-content imaging myths
High-content imaging has become a cornerstone of life science research, providing valuable insights into cellular function and drug responses. However, as with any advanced technology, misconceptions and myths can emerge. In this article, we’ll debunk some of the most common myths surrounding high-content imaging, shedding light on its true strengths and limitations.
Application Note
Kinetic analysis of calcium flux activity in human iPSC-derived neurons using the Opera Phenix Plus system
Application note for fast kinetic imaging using HCS to visualize and evaluate spontaneous calcium flux activity in single human iPSC-derived neurons
Case Study
Improving the throughput of a neuroprotection assay using the opera phenix high content screening system
Download the case study to learn how primary neuron morphology is analyzed in a straightforward approach using Harmony® software and careful assay optimization can increase throughput, and minimize the data burden, without compromising assay performance.
Case Study
Re-tooling anti-microbial research for the 21st century
Case study describing the analysis of bacterial phenotypes to investigate adaptive mechanisms of antimicrobial resistance and screening for novel alternatives.
Technical Note
Opera Phenix Plus high-content screening system: crosstalk suppression
Technical note describing how fluorescent crosstalk is suppressed by the Opera Phenix Plus high-content screening system.
Literature - Publication Review
Organ-on-chips: increased complexity for higher physiological relevance in pharmaceutical safety testing
Explore the advancements of liver and kidney-on-chip models, and how these platforms effectively simulate toxicity responses.
Literature - Publication Review
Morphological profiling of human T and NK lymphocytes by high-content imaging
The study in this publication review provides a foundation for the development of morphological profiling as a scalable approach to monitor the immune synapse (IS), primary lymphocyte responsiveness and microarchitecture.
Literature - Publication Review
Multifunctional mRNA-based CAR T-cells show promising anti-tumor activity against glioblastoma
Learn how researchers have evaluated the efficiency of mRNA-based multifunctional CAR T-cells against glioblastoma in vitro and in vivo.
Literature - Publication Review
Imaging and gene editing approaches highlight important role of autophagy in controlling Mtb infection
Learn how researchers used CRISPR-Cas9 gene editing and high-content imaging approaches to explore the role of autophagy in controlling Mtb infection.
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