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LANCE Ultra Mouse IL-6 Detection Kit, 10,000 Assay Points

Lance Ultra Detection Kit
LANCE Ultra Mouse IL-6 Detection Kit, 10,000 Assay Points
Lance Ultra Detection Kit
Lance Ultra Detection Kit
Lance Ultra Detection Kit
Lance Ultra Detection Kit
Lance Ultra Detection Kit

The LANCE® Ultra Mouse IL-6 Detection Kit is designed for detection and quantitation of murine IL-6 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

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Feature Specification
Application Protein Quantification
Dynamic Range 8.2- 30,000 pg/mL  
Limit of Detection 8.2 pg/mL  
Limit of Quantification 42.5 pg/mL  
Sample Volume 15 µL
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The LANCE® Ultra Mouse IL-6 Detection Kit is designed for detection and quantitation of murine IL-6 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

Click to copy promo code to clipboard.
March lab savings - SAVE 10%. Use promo code below.
MARCH10
Terms and conditions apply.
View product information
Product Variants
Unit Size: 500 assay points
Part #:
TRF1504C
List Price
USD 1,245.32
Your online price:
Unit Size: 10,000 assay points
Part #:
TRF1504M
List Price
USD 16,483.48
Your online price:
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption, and disposal requirements under European REACH regulations (EC 1907/2006).
Total list price:
USD 16,483.48
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Lance Ultra Detection Kit
Lance Ultra Detection Kit
LANCE Ultra Mouse IL-6 Detection Kit, 10,000 Assay Points
Lance Ultra Detection Kit
Lance Ultra Detection Kit
Lance Ultra Detection Kit
LANCE Ultra Mouse IL-6 Detection Kit, 10,000 Assay Points
Lance Ultra Detection Kit
Lance Ultra Detection Kit

Product information

Overview

The LANCE Ultra Mouse IL-6 Detection Kit is designed for detection and quantitation of murine IL-6 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.

The 500 point kit contains enough reagents to run 500 wells in 384-well format, using a 20 µL reaction volume (15 µL of sample). The 10,000 point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 µL reaction volume (15 µL of sample).

  • No-wash steps, no separation steps
  • TR-FRET technology
  • Sensitive detection
  • High reproducibility
  • Faster time-to-results
  • Easy automation
  • 96-well, 384-well, and 1536-well formats

LANCE and LANCE (Lanthanide chelate excite) Ultra are our TR-FRET (time-resolved fluorescence resonance energy transfer), homogeneous (no wash) technologies. One antibody of interest is labeled with a donor fluorophore (a LANCE Europium chelate) and the second molecule is labeled with an acceptor fluorophore (ULight™ dye). Upon excitation at 320 or 340 nm, energy can be transferred from the donor Europium chelate to the acceptor fluorophore if sufficiently close for FRET (~10 nm). This results in the emission of light at 665 nm.

In the mouse, Interleukin 6 (IL6) is a 187 amino acid cytokine. In humans, IL6 is produced by a variety of cell types, including T-cells, mast cells, and monocytes. IL6 signals through binding to the gp130/ IL6R receptor complex. IL6 acts not only on the immune system, but also affects many physiological events in various organs. IL6 exerts pro- or antiinflammatory responses, depending on the target cell analyzed and the in vivo environmental circumstances. IL6 is a differentiation and proliferation factor for B and T cells, and acts as a migration factor on monocytic cells. It is the major activator of acute-phase protein expression in the liver and acts as a survival factor on neuronal cells. Elevated serum IL6 levels have been observed during bacterial and viral infection, trauma, autoimmune disease, inflammation, and cancer.

Specifications

Application
Protein Quantification
Automation Compatible
Yes
Brand
LANCE Ultra
Detection Modality
LANCE
Dynamic Range
8.2- 30,000 pg/mL  
Limit of Detection
8.2 pg/mL  
Limit of Quantification
42.5 pg/mL  
Product Group
Kit
Sample Volume
15 µL
Shipping Conditions
Shipped in Blue Ice
Target
IL6
Target Class
Cytokines
Target Species
Mouse
Technology
TR-FRET
Therapeutic Area
Inflammation
Unit Size
10,000 assay points

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