Learn about our world class antibodies for a diverse set of research areas including immunology, neuroscience, cancer, stem cells and cell biology.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Driving meaningful innovation that profoundly impacts science and human lives.
Driving meaningful innovation that profoundly impacts science and human lives.
Driving meaningful innovation that profoundly impacts science and human lives.
Driving meaningful innovation that profoundly impacts science and human lives.
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Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
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Altered signaling pathways are involved in many cancer types, adding fuel to processes associated with uncontrolled growth and an increased ability to invade surrounding tissue. In order to develop efficient therapies to fight cancers, scientists must study how these dysregulated pathways respond to the drug candidate.
One of these pathways is FGFR mediated PLCγ signaling, identified in breast and prostate cancers. Inositor Triphosphate (IP3) is a signaling molecule in this pathway, and its metabolization results in D-myo-Inositol 1-Phosphate (IP1).
In this application note, scientists show how the detection of intracellular accumulation of IP1 can be used as a powerful way to characterize compounds modulating FGF receptor signaling in various cancer cell lines expressing FGFR1, FGFR2, and FGFR3.
Using our no-wash and automatable IP-One HTRF™ and AlphaLISA™ assays, scientists measured the activation status of intracellular downstream key enzymes and second messengers.
Featured in this application note:
For research use only. Not for use in diagnostic procedures.
Using IP1 assays to study FGFR mediated pathways for cancer drug research