Learn about our world class antibodies for a diverse set of research areas including immunology, neuroscience, cancer, stem cells and cell biology.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.
Driving meaningful innovation that profoundly impacts science and human lives.
Driving meaningful innovation that profoundly impacts science and human lives.
Driving meaningful innovation that profoundly impacts science and human lives.
Driving meaningful innovation that profoundly impacts science and human lives.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
Quickly find and download manuals, safety documents, certificates of analysis and more.
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G protein-coupled receptors (GPCRs) are a large family of transmembrane receptors that are significant drug targets. They function as enzymes that activate G-proteins. GPCRs couple to three main families of Gα subunits: Gαi/o, Gαs, and Gαq.
The coupling specificity depends on the GPCR and its cellular environment. Gαs and Gαi subunits operate through the cAMP pathway, either activating or inhibiting adenylate cyclase, which converts ATP to cAMP.
In this application note, the AlphaScreen™-based cAMP detection technology has been used to study Gαi-coupled receptors, specifically the 5-hydroxytryptamine-1A (5-HT1A) serotonergic receptor. The note demonstrates the utility of the AlphaScreen-based cAMP Assay kit for the pharmacological characterization and potential high-throughput screening of Gαi-coupled receptors.
For research use only. Not for use in diagnostic procedures.
cAMP AlphaScreen assay: a method for the pharmacological characterization and screening of Gαi coupled receptors in whole cells