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Application Note
A fast and simple chemiluminescent assay for monitoring of DNA-protein interactions
In this application note, we use HepG2 nuclear extracts to demonstrate the binding of Sp1 and HNF1 transcription factors to tagged oligonucleotides containing required cognate response elements. Read this note to see the results and access detailed data compared to EMSA.
Application Note
Characterizing chemokine receptor inhibitors with AlphaLISA SureFire Ultra, Alpha SureFire Ultra Multiplex and LANCE Ultra cAMP assays
This application note demonstrates how the SureFire Ultra and LANCE Ultra cAMP assays can be used for measuring inhibitors to CCR7 and CXCR2 cell surface receptors using a cellular model system where these receptors are overexpressed in CHO cells.
Product Info
LANCE and LANCE Ultra TR-FRET technology product list
LANCE™ Ultra is a highly sensitive and highly reproducible no-wash proximity assay technology that combines the benefits of time resolution (TR) with fluorescence resonance energy transfer (FRET).
Whitepaper
Targeted protein degradation: A novel therapeutic strategy for neurodegenerative diseases
In this white paper, get details about TPD that offers a novel strategy for neurodegenerative diseases by degrading disease-linked proteins, showing promise in preclinical studies.
Technical Note
A simple method for preparing GPCR membrane model extracts from stable cell lines for use with the HTRF GTP Gi binding assay
This Technical Note provides a detailed method for preparing GPCR membrane model extracts from stable cell lines for use with the HTRF GTP Gi binding assay, including cell culture preparation, cell lysis, membrane extraction, and assay optimization.
Application Note
Comparison of EMT Biomarker Expression in 2D Monolayer and 3D Spheroid Cultures in a Prostate Cancer
This application note shows that AlphaLISA can be used to compare differences in protein expression levels and cellular tolerance for compound treatment between a human prostate cancer cell line grown in monolayers and those same cells grown in 3D spheroids.
Brochure
Get Our Brochure on Luminescence Assay Technology
Get Revvity’s brochure on advanced luminescence assay technology, featuring high sensitivity and dynamic range for gene expression, cell viability, and drug development.
Flyer
Download your ATPlite flyer
Revvity offers ATPlite™ and ATPlite 1step assays to measure cellular ATP levels, indicating cell viability and proliferation, using firefly luciferase and D-luciferin. Check out our flyer for the latest solutions in cytotoxicity, cell viability, and cell proliferation assays.
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