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Application Note
Developing novel tetraubiquitin substrates and AlphaLISA technology to provide next generation deubiquitinase assays
This application note presents novel biochemical DUB assays that use TUBEs to bind to tetraubiquitin substrates of at least three natural linkages. These assays, combined with Revvity’s AlphaLISA™ technology, allow for the measurement of protein interactions and large protein complexes in a no-wash, homogeneous assay.
Application Note
Detection of human matrix metalloproteinase 9 in complex sample matrices, a comparison of AlphaLISA and colorimetric ELISA immunoassays
This note compares two immunoassay technologies: ELISA (enzyme-linked immunosorbent assay) and AlphaLISA™ (amplified luminescent proximity-based homogeneous assay).
Infographic
Precision medicine research, for sharper decisions
Precision medicine can lead to sharper decision making through functional and molecular stratification.
Whitepaper
Genetically engineered PDX models as patient avatars in preclinical evaluation of acute leukemias
Identifying therapeutic targets using gene silencing techniques in PDX models
Flyer
Cellometer Spectrum image cytometer flyer
Flyer summarizing the Cellometer Spectrum image cytometer.
Literature - Publication Review
Spleen-targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma
Researchers used the IVIS Spectrum and IVISbrite D-luciferin substrate to investigate how a spleen-targeted DNA vaccine, delivered via RBC-hitchhiked nanoparticles, effectively induced robust neoantigen specific T cell responses in HCC.
Whitepaper
Leveraging next-generation cell line development technologies for cost-effective biotherapeutic applications
Reviewing the transformative innovations within the cell line development process to help improve biotherapeutics.
Scientific Poster
CHOSOURCE ADCC+ cell line for enhanced therapeutic potency
Discover how the CHOSOURCE ADCC+ cell line increases Antibody Dependent Cellular Cytotoxicity (ADCC) for use in the production of biotherapeutics for oncology, anti-infectives and auto-immune diseases.
Scientific Poster
Application of gene editing technologies to improve biotherapeutic manufacturing
Showcasing a multiplex gene editing approach with well-defined workflows and established tools to isolate, identify, and characterize edited knock-out or knock-in clones in different cell types.
Scientific Poster
Integration of next-generation transposon vectors with state-of-the-art host cell lines
Presenting the performance data of CHOSOURCE TnT expressing a standard immunoglobulin G (IgG) molecule with CHOSOURCE CHO-K1 GS KO and ADCC+ cell lines
Webinar
CHOSOURCE™ GS KO cell line: optimization, improvement strategy, and case study
On-demand webinar showing how to enhance bioprocess in CHO cell lines through molecular design, screening, and process optimization strategies, utilizing the CHOSOURCE expression platform.
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