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Product Note
Scientific Poster
CHOSOURCE ADCC+ cell line for enhanced therapeutic potency
Discover how the CHOSOURCE ADCC+ cell line increases Antibody Dependent Cellular Cytotoxicity (ADCC) for use in the production of biotherapeutics for oncology, anti-infectives and auto-immune diseases.
Scientific Poster
Application of gene editing technologies to improve biotherapeutic manufacturing
Showcasing a multiplex gene editing approach with well-defined workflows and established tools to isolate, identify, and characterize edited knock-out or knock-in clones in different cell types.
Scientific Poster
Integration of next-generation transposon vectors with state-of-the-art host cell lines
Presenting the performance data of CHOSOURCE TnT expressing a standard immunoglobulin G (IgG) molecule with CHOSOURCE CHO-K1 GS KO and ADCC+ cell lines
Webinar
CHOSOURCE™ GS KO cell line: optimization, improvement strategy, and case study
On-demand webinar showing how to enhance bioprocess in CHO cell lines through molecular design, screening, and process optimization strategies, utilizing the CHOSOURCE expression platform.
Whitepaper
Advancing biotherapeutic development with transposon-based technologies
Discover how to generate highly producing pools early on in your development workflow with transposon technology and accelerate time to clinic
Whitepaper
The evolving landscape of quality by design in biologics manufacturing
Implement QbD principles to meet safety, efficacy, and consistency challenges in biologics manufacturing
Whitepaper
Maximizing returns in biotherapeutic investment: Financial considerations for expression systems
Helping examine the key economic factors when selecting expression systems that impact quality, quantity, and cost-effectiveness for biotherapeutic production.
Application Note
Effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in high-content analysis screening experiments
Find out about the effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in HCA screening experiments.
Application Note
Pooled phenotypic CRISPR screening enables the identification of synergistic drug combinations for cancer therapy
This application note demonstrates how a pooled phenotypic CRISPR screening can be used to identify synergistic drug combinations for cancer therapy
Literature - Publication Review
Linking genes to phenotypes with CRISPR screening
Literature review on the multiple CRIPSR screening techniques available for drug discovery and their benefits.
Whitepaper
Overcoming hurdles in high-throughput profiling of cancer cell responses
Presenting case studies on how functional genomic screening is used to find therapeutic targets, identify patient populations, uncover MoA, investigate drug combinations, and reveal drug resistance and sensitivity
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