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Article
Assessing nanomedicine delivery across the blood-brain barrier using pre-clinical in vivo imaging
Researchers discuss the rationalrationale behind utilizing various pre-clinical in vivo imaging techniques to explore the uptake of custom-designed nanomedicines at different stages of brain cancer.
Application Note
Developing novel tetraubiquitin substrates and AlphaLISA technology to provide next generation deubiquitinase assays
This application note presents novel biochemical DUB assays that use TUBEs to bind to tetraubiquitin substrates of at least three natural linkages. These assays, combined with Revvity’s AlphaLISA™ technology, allow for the measurement of protein interactions and large protein complexes in a no-wash, homogeneous assay.
Product Note
IVIS Lumina X5 product note
High-sensitivity 2D optical meets high-resolution x-ray with the IVIS Lumina X5 benchtop imaging system.
Product Note
IVIS Lumina S5 product note
Flexible and sensitive 2D optical imaging in a benchtop format with the IVIS Lumina S5 system.
Product Note
IVIS Spectrum Product note
2D and 3D preclinical optical imaging with the industry-leading IVIS® Spectrum system.
Product Note
IVIS SpectrumCT product note
The IVIS SpectrumCT bioluminescence and fluorescence preclinical imaging system with integrated CT.
Application Note
Detection of human matrix metalloproteinase 9 in complex sample matrices, a comparison of AlphaLISA and colorimetric ELISA immunoassays
This note compares two immunoassay technologies: ELISA (enzyme-linked immunosorbent assay) and AlphaLISA™ (amplified luminescent proximity-based homogeneous assay).
Brochure
A whole new perspective on ultrasound imaging
Introducing Vega®, automated, hands-free, high-throughput ultrasound for preclinical research.
Literature - Publication Review
Expert interview: recapitulating the blood-brain barrier using in vitro hiPSC models in drug discovery
Better understand the blood-brain barrier for translational research and drug discovery in neurodegenerative diseases.
Whitepaper
Genetically engineered PDX models as patient avatars in preclinical evaluation of acute leukemias
Identifying therapeutic targets using gene silencing techniques in PDX models
Infographic
Why 3D: stripping complexity out of multi-dimensional cell models
Bridging the gap between 2D Cell cultures and in vivo conditions.
Literature - Publication Review
Exploring mechanisms behind alphavirus-induced post-encephalitic parkinsonism
neuroinvasive viruses eliciting neurodegenerative symptoms of post-encephalitic parkinsonism by using bioluminescent or fluorescent recombinant WEEV in an in vivo mouse model
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