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Whitepaper
Genetically engineered PDX models as patient avatars in preclinical evaluation of acute leukemias
Identifying therapeutic targets using gene silencing techniques in PDX models
Whitepaper
Advancing biotherapeutic development with transposon-based technologies
Discover how to generate highly producing pools early on in your development workflow with transposon technology and accelerate time to clinic
Whitepaper
The evolving landscape of quality by design in biologics manufacturing
Implement QbD principles to meet safety, efficacy, and consistency challenges in biologics manufacturing
Whitepaper
Maximizing returns in biotherapeutic investment: Financial considerations for expression systems
Helping examine the key economic factors when selecting expression systems that impact quality, quantity, and cost-effectiveness for biotherapeutic production.
Whitepaper
Preclinical screening platforms for antibody-drug conjugate therapeutics
Learn more about ADCs and the role that screening can play to help advance the discovery process for ADC therapeutic candidates in this white paper.
Whitepaper
Sugar with your protein? - Generation of a fucosylation-deficient CHO cell host to produce therapeutics with enhanced potency
Detailed overview of how CHO cells have been genetically modified to enable production of afucosylated antibodies with enhanced ADCC activity for improved biotherapeutics
Whitepaper
Harnessing cell line engineering to enhance biotherapeutics
Exploring the next-generation genome editing tools that are helping drive the success of monoclonal antibodies as biotherapeutics
Whitepaper
Achieving higher throughput for the bioanalysis of advanced biotherapeutics
With advanced biotherapeutics requiring characterization and stringent quality control, read how by assessing critical quality attributes early within cell line development you can improve your chances in clinic
Whitepaper
Efficient multiplexed targeted gene editing as a strategy to generate improved CHO host cell lines for biotherapeutic manufacturing applications
Learn about Revvity’s capabilities to simultaneous edit genes using CRISPR-Cas9 that incorporates stringent genetic QC steps for comprehensive characterization.
Whitepaper
Deconstructing and leveraging 3D structures of RNAs for novel therapeutics
A research team has engineered degradation-resistant mRNAs which could hold promise for treating various neurodegenerative disorders.
Whitepaper
Leveraging next-generation cell line development technologies for cost-effective biotherapeutic applications
Reviewing the transformative innovations within the cell line development process to help improve biotherapeutics.
Whitepaper
Establishing an automated high-throughput assay that supports the growth of prostate cancer organoids
Researchers concluded that their study demonstrates the ability to automate preclinical testing with prostate cancer organoids with diverse phenotypes.
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