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Leveraging next-generation cell line development technologies for cost-effective biotherapeutic applications
Reviewing the transformative innovations within the cell line development process to help improve biotherapeutics.

An emerging therapeutic modality - RNA carves its path out of the paradigm
Learn more about several promising classes of RNA therapeutic, including RNAi, CRISPR, base editing, and mRNA vaccines, as well as the potential to combine RNA technologies with CAR-T.

Advancing biotherapeutic development with transposon-based technologies
Discover how to generate highly producing pools early on in your development workflow with transposon technology and accelerate time to clinic

The evolving landscape of quality by design in biologics manufacturing
Implement QbD principles to meet safety, efficacy, and consistency challenges in biologics manufacturing

Optimizing AAV manufacturing: a scalable harvest protocol
As demand for recombinant AAV (rAAV) vectors continues to rise, scalable and efficient manufacturing processes are essential for advancing gene therapy.

Maximizing returns in biotherapeutic investment: Financial considerations for expression systems
Helping examine the key economic factors when selecting expression systems that impact quality, quantity, and cost-effectiveness for biotherapeutic production.

ImmuSignature™ MLR: Rapid high-throughput assessment of therapeutic immunogenicity
This white paper describes how a rapid immunogenicity assessment screening can provide invaluable support for IND applications.

Assessing the epigenetics of T cell exhaustion using CRISPR screens
Explore the epigenetics of T cell exhaustion and practical techniques to assess immune cell epigenetic regulators using CRISPR screens.

Base editing and stem-cell based therapies
This white paper explores how base editing is advancing iPSCs in the fields of basic science, regenerative medicine and immunotherapy.

Addressing the challenges in solid tumor therapy with base editing
Read this white paper to learn about how base editing is helping to address key challenges in immunotherapies for solid tumors.

Finding the right technology for your genome engineering project
Learn about how to select the right technology for your genome engineering project in this white paper.

Generating a clonal HAP1LIG4(-) Cas9(+) cell line – an expert interview
An interview with Dr. Gerety, the Sanger Institute on generating a new HAP1 cell line and how it can help advance scientific discovery.


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