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Transforming preclinical leukemia research with no-wash immunoassays for BRD4-targeted degradation
This application note explores how HTRF based immunoassays enhance BRD4-targeted degradation studies, providing insights into leukemia research and accelerating drug discovery.
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Multi-parametric assessment of EGF treatment effects on signaling pathways, growth and proliferation using AlphaLISA SureFire Ultra and cellular imaging
Application note demonstrating an efficient cell-based workflow for the assessment of EGF treatment effects using no-wash AlphaLISA® SureFire® Ultra assays and cellular imaging.
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Multi-parametric high-throughput analysis of hepatotoxicity using a 3D primary liver cell culture model
The creation of an advanced 3D primary human hepatocyte (PHH) model using the RASTRUM platform that seamlessly integrates with Revvity’s HTS technologies.
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Evaluation of drug selectivity and efficacy using PROTACs in a 3D co-culture spheroid model
The aim of this study was to evaluate the efficacy and selectivity of SJF1528, a pan-EGFR PROTAC, and MS39, a mutant-specific EGFR L858R PROTAC, while exploring the use of both high-content imaging and no-wash HTRF immunoassays in encapsulated 3D spheroid models.
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Embryo Identification, tracking and contamination monitoring using Mitochondrial SNVs.
Embryo Identification, tracking and contamination monitoring using Mitochondrial SNVs.
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