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Application Note
DNA extraction from Turbatrix aceti using the Omni Bead Ruptor 4 bead mill homogenizer
Rapid DNA extraction from nematodes using bead mil homogenization.
Application Note
High-throughput RNA extraction from Mus musculus tissues on the Omni Bead Ruptor 12 bead mill homogenizer
Technical performance comparison of bead milling vs cryomilling with mortar and pestle from mouse tissue
Application Note
High-throughput lysis of E. coli for multiple analytes using the Omni Bead Ruptor 96 bead mill homogenizer
Omni Bead Ruptor 96 enhances bacterial lysis and recovery of DNA, RNA, and proteins for high-throughput, well-plate sample homogenization and lysis
Application Note
Total protein quantification from murine teeth using the Omni Bead Ruptor 96 homogenizer
Optimization of murine teeth homogenization for proteomic analysis using bead milling.
Application Note
High-throughput mosquito DNA extraction and PCR analysis on the Omni Bead Ruptor 96 bead mill homogenizer
High-throughput mosquito DNA extraction and PCR analysis using bead-beating tubes and well-plate homogenizer
Application Note
High-throughput genomic DNA and protein extraction from multiple tissue types using the Omni Bead Ruptor 96 bead mill homogenizer
High-throughput DNA and protein extraction from multiple tissues using well-plate homogenizer using a well-plate homogenizer
Application Note
Inhibition of FGFR signaling pathways studied in cancer cell lines using HTRF
In this application note, we show that a pan-FGFR inhibitor, AZD4547, used in different clinical phases depending on the cancer type, is able to inhibit or even suppress the abnormal phosphorylation of FGFRs and their key effectors in 3 different types of cancer cell lines: KG-1 (blood cancer), SNU-16 (gastric cancer), and KMS-11 (multiple myeloma).
Application Note
HTRF assays handle low- to high affinity protein-protein interactions
This application note demonstrated that HTRF PPI reagents are successfully used combining high detection performance, accurate modulators screening, and pharmacological characterization.
Application Note
HTRF addresses large protein-protein interaction complexes
This application note demonstrates the applicability of HTRF to PPIs, without restrictions on the sizes or MW of the complexes probed.
Application Note
TCR phospho signaling investigation with HTRF
In this Note, we used HTRF phospho assays to study specific and ubiquitous proteins in the TCR pathway (ZAP70, SLP76, ERK …) in Peripheral Blood Mononuclear Cells (PBMC) and isolated T cells both under stimulation and in checkpoint inhibition conditions.
Application Note
Characterization of candidate molecules through GTP binding assays
Discover the characterization process for candidate molecules targeting Gα-protein activation through GPCRs with the functional HTRF® GTP binding assays.
Application Note
Harness avidity without compromising on pharmacology
Learn about the differential effect of the biot-SA system while maintaining accurate pharmacological characterization.
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