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Cell cycle infographic
Targeting various steps of the cell cycle is a promising strategy for cancer therapeutics. Learn more from our infographic.
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Protein recycling, TPD, and neurodegenerative disease
Targeted protein degradation (TPD) via the proteasomal and lysosomal pathways is a promising therapeutic approach that represents a novel tool for exploring cellular pathways. TPD offers several key advantages over traditional occupancy-based inhibitors, notably concerning dosing, drug resistance, and side effects.
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DELFIA VICTOR Immunoassays- How to Optimize Rapid and Simple Immunoassays
In this application note, parameters affecting the performance characteristics of rapid and simple immunoassays have been optimized. These parameters were temperature, concentration of immunocomponents, dynamics (including diffusion), and the quality of immunocomponents.
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Developing novel tetraubiquitin substrates and AlphaLISA technology to provide next generation deubiquitinase assays
This application note presents novel biochemical DUB assays that use TUBEs to bind to tetraubiquitin substrates of at least three natural linkages. These assays, combined with Revvity’s AlphaLISA™ technology, allow for the measurement of protein interactions and large protein complexes in a no-wash, homogeneous assay.
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Detection of human matrix metalloproteinase 9 in complex sample matrices, a comparison of AlphaLISA and colorimetric ELISA immunoassays
This note compares two immunoassay technologies: ELISA (enzyme-linked immunosorbent assay) and AlphaLISA™ (amplified luminescent proximity-based homogeneous assay).
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Precision medicine research, for sharper decisions
Precision medicine can lead to sharper decision making through functional and molecular stratification.
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The impact of no-call rate in NIPT
A reference that highlights the clinical importance of no-call rate in NIPT (non-invasive prenatal testing).
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HMGB1, IL-1β and IL-18 assays used together to discriminate pyroptosis and necroptosis
This application note shows that the release of HMGB1 induced in the context of pyroptosis and necroptosis can be easily monitored with the HTRF® HMGB1 kit.
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Download your application note on fibrosis characterization
This note describes deep investigations of the molecular mechanisms involved in tissue fibrosis, and occurring in the major effector cell types.
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Download your application note on nuclear receptor ligand identification with HTRF
This application note illustrates the use of HTRF PPI reagents to easily build robust and convenient biochemical NR/ CoA recruitment assays.
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The Story of Gene Therapy
This infographic gives you a short but clear insight into how gene therapies work.
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