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Expert interview: cancer resistance to immunotherapy
Understand the Mechanisms behind Cancer Resistance to Immunotherapy
Brochure Icon   Brochure
Pooled functional genomic screening solutions and services
Functional genomic screening has the potential to reshape drug discovery, enhance our understanding of biological systems, and revolutionize personalized medicine.
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Selective targeting of mHTT presents novel therapeutic approach to huntington's disease
Researchers have engineered zinc finger protein transcription factors (ZFP-TFs) to target the pathogenic CAG repeat and selectively lower mHTT as a therapeutic strategy.
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Learning from our ancestors: can we be better prepared for the next pandemic?
Researchers have found evidence of an ancient viral epidemic involving host coronavirus interacting genes in East Asia more than 20,000 years ago. These findings could help countries prepare for future pandemics.
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Meet the scientist: uncovering the pathways dictating evolution of lung cancer heterogeneity
Understanding why tumors evolve from a single cell to a heterogenous tissue could direct the development of new therapies.
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Precision medicine research, for sharper decisions
Precision medicine can lead to sharper decision making through functional and molecular stratification.
Publication Icon   Literature - Publication Review
Expert interview: recapitulating the blood-brain barrier using in vitro hiPSC models in drug discovery
Better understand the blood-brain barrier for translational research and drug discovery in neurodegenerative diseases.
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AAV vectors: Pursuing a one-time therapy for ocular diseases
Explore the latest advancements in gene therapy and its transformative impact on ocular health.
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Innovative approaches for advancing genetic payload development
Discover the future of gene therapy in our white paper 'Innovative approaches for advancing genetic payload development.' Learn about the challenges and breakthroughs in gene editing, offering a glimpse into the evolving landscape of genetic medicine.
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ImmuSignature™ MLR: Rapid high-throughput assessment of therapeutic immunogenicity
This white paper describes how a rapid immunogenicity assessment screening can provide invaluable support for IND applications.
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Assessing the epigenetics of T cell exhaustion using CRISPR screens
Explore the epigenetics of T cell exhaustion and practical techniques to assess immune cell epigenetic regulators using CRISPR screens.
Application Note Icon   Application Note
Rapid screening of novel therapeutics by ImmuSignature™ T cell activation assay
This application note describes the development of a robust T cell activation assay to assess the impact of novel therapeutics on T cell function.
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