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CHOSOURCE expression platform
Helping you confront biotherapeutic challenges with a robust CHO expression platform without constraints.

Maximizing returns in biotherapeutic investment: Financial considerations for expression systems
Helping examine the key economic factors when selecting expression systems that impact quality, quantity, and cost-effectiveness for biotherapeutic production.

Advancing biotherapeutic development with transposon-based technologies
Discover how to generate highly producing pools early on in your development workflow with transposon technology and accelerate time to clinic

Harnessing cell line engineering to enhance biotherapeutics
Exploring the next-generation genome editing tools that are helping drive the success of monoclonal antibodies as biotherapeutics

Achieving higher throughput for the bioanalysis of advanced biotherapeutics
With advanced biotherapeutics requiring characterization and stringent quality control, read how by assessing critical quality attributes early within cell line development you can improve your chances in clinic

Sugar with your protein? - Generation of a fucosylation-deficient CHO cell host to produce therapeutics with enhanced potency
Detailed overview of how CHO cells have been genetically modified to enable production of afucosylated antibodies with enhanced ADCC activity for improved biotherapeutics

Efficient multiplexed targeted gene editing as a strategy to generate improved CHO host cell lines for biotherapeutic manufacturing applications
Learn about Revvity’s capabilities to simultaneous edit genes using CRISPR-Cas9 that incorporates stringent genetic QC steps for comprehensive characterization.

Leveraging next-generation cell line development technologies for cost-effective biotherapeutic applications
Reviewing the transformative innovations within the cell line development process to help improve biotherapeutics.

Protein extraction from rat tissue using Omni Bead Ruptor 4
Multi-sample bead mill homogenization for protein extraction from rat tissue - muscle, brain, liver, heart

Proinflammatory cytokine evaluation from human PBMCs in response to AAV8 peptides
This application note discusses the evaluation of proinflammatory cytokines from human PBMCs in response to AAV8 peptides using HTRF and ELISpot technologies. It highlights the methodology, results, and significance of cytokine profiling in the context of gene therapy.

Streamlining the development of bispecific antibodies from expression to quality assessment with Revvity’s biotherapeutic workflow solutions
Expression and characterization of bispecific antibodies with a combination of CHOSOURCE TnT Transposon Technology and LabChip to streamline biotherapeutic workflows

Monitoring residual HEK293 DNA in AAV-based therapies using the HostDetect HEK293 PCR DNA quant kit
Data behind the development of the HostDetect Hek293 kit that offers a PCR-based approach for quantifying residual host cell DNA


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