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Whitepaper
Addressing the challenges of bispecific antibody characterization with high-throughput platforms
With the complexities of bispecific antibody development and characterization explore the binding assays and technology through real-world examples
Whitepaper
Murine NASH model could provide insights into NASH development and progression
Researchers explore a multidisciplinary approach to addressing current NAFLD and NASH challenges.
Technical Note
AlphaLISA Acetyl‑Histone H3 lysine 9 (H3K9ac) cellular assay
This technical note provides information on how the AlphaLISA immunodetection assay detects variations in acetylated histone H3 lysine 9 (H3K9ac) levels within cellular extracts
Technical Note
Assessing AST released in a cell culture model of liver toxicity using AlphaLISA
In this technical note, we showcase the utility and advantages of using AlphaLISA assays to identify and quantify AST protein levels in cellular lysate and supernatant from a human hepatoma cell line
Technical Note
AlphaLISA for biomarkers in urine: Measuring the renal tubular injury indicator, β2-microglobulin
In this study, AlphaLISA™ technology is demonstrated for the first time in the complex matrix of urine, and is shown to detect the renal tubular injury marker Beta2-microglobulin (β2-microglobulin), in urine at a sensitivity
Article
Busting high-content imaging myths
High-content imaging has become a cornerstone of life science research, providing valuable insights into cellular function and drug responses. However, as with any advanced technology, misconceptions and myths can emerge. In this article, we’ll debunk some of the most common myths surrounding high-content imaging, shedding light on its true strengths and limitations.
eBook
Upscaling organoid research for sharper biological insights
To scale up, standardize and achieve greater biological insights, researchers need to rely on automation and multi-dimensional datasets.
Technical Note
Designing your own AlphaLISA assay: Selecting toolbox bead pairs to avoid potential bead-bead interactions
This technical note provides recommendations on bead pairings, highlighting host species of antibodies on each toolbox bead, along with data generated in the absence of analyte and other assay components.
Technical Note
3D volumetric and zonal analysis of solid spheroids
Technical note describing how to image and analyze solid spheroids in 3D.
Technical Note
DNA Quantification Using the VICTOR Nivo and Micro-Volume Plates
We highlight the VICTOR Nivo’s robust capability to quantify DNA concentration using micro-volume plates in three experiments.
Application Note
Label-free analysis of cardiomyocyte beating using the Opera Phenix Plus System
Learn how to reliable quantify cardiomyocyte beating frequency using the Opera Phenix Plus high-content screening system in this application note.
Technical Note
Clearing strategies for 3D spheroids
In this technical note, we compare optical clearing strategies for 3D spheroids and demonstrate how to increase imaging depth in 3D spheroids by a factor of 4.
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