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The Pin-point™ platform: A novel modular base editing system
This presentation provides an overview of the Pin-point base editing platform by describing its key benefits, how it works, and supporting data.

The future of immunotherapy gets brighter with base editing
This literature review discusses how base editing technology addresses the shortcomings of other gene editing technologies for immunotherapy.

Base editing and stem-cell based therapies
This white paper explores how base editing is advancing iPSCs in the fields of basic science, regenerative medicine and immunotherapy.

Addressing the challenges in solid tumor therapy with base editing
Read this white paper to learn about how base editing is helping to address key challenges in immunotherapies for solid tumors.

A single-step process for engineering hypoimmunogenic pluripotent stem cells with the Pin-point™ platform
Learn about the utility of the Pin-point™ base editing platform for the engineering of allogeneic PSCs.

Interchanging Cas enzymes, deaminases, and aptamerguide RNA combinations to achieve optimal editing with the modular Pin-point™ base editing platform
Learn how to apply multiplex base editing to efficiently develop engineered CAR-T cells and hypoimmunogenic iPSCs.

Base editing with nuclease flexibility
In this application note, we demonstrate how the Pin-point™ base editing platform’s modularity allows for its components to be optimized to the target site.

One-step engineering of allogeneic cell therapies with Pin-point base editing platform and an AI-engineered Cas enzyme
This scientific poster describes a one-step process to engineer allogeneic cell therapies with the Pin-point base editing platform and an AI-engineered Cas enzyme.

A versatile base editing technology with broad Cas enzyme and deaminase compatibility well suited for Cell and Gene Therapy
This scientific poster describes the development of a versatile base editing platform for cell and gene therapy.

Development and validation of customized guide RNA design and efficiency prediction tools for the Pin-point base editing platform
This scientific poster describes the development and validation of customized guide RNA design and efficiency prediction tools for the Pin-point base editing platform.

Complex genome engineering with the Pin-point base editing system
This application note describes how Pin-point base editing platform can be applied to complex gene editing, even in sensitive cell types.

Finding the right technology for your genome engineering project
Learn about how to select the right technology for your genome engineering project in this white paper.


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