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LabChip Plasmid DNA (pDNA) Assay

The LabChip™ Plasmid DNA assay is designed to streamline your plasmid (pDNA) workflows. It separates the three primary isoforms of pDNA in under 2 minutes/sample while providing purity assessment based on the corrected area percentages for each conformation.

Each kit contains enough reagents for 20 chip preps. A maximum of 24 samples can be run per each chip prep.

Key Features:

  • Separates supercoiled, linear, and open circular pDNA
  • Uses a plasmid DNA sample input concentration from 50 to 500 pg/µL
  • Combo ladder offers simultaneous sizing of supercoiled and linear isoforms
  • Detects impurities down to 25 pg/µL
  • Sample input size range 2-13kb
  • 21 CFR Part 11 capable
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The LabChip™ Plasmid DNA assay is designed to streamline your plasmid (pDNA) workflows. It separates the three primary isoforms of pDNA in under 2 minutes/sample while providing purity assessment based on the corrected area percentages for each conformation.

Each kit contains enough reagents for 20 chip preps. A maximum of 24 samples can be run per each chip prep.

Key Features:

  • Separates supercoiled, linear, and open circular pDNA
  • Uses a plasmid DNA sample input concentration from 50 to 500 pg/µL
  • Combo ladder offers simultaneous sizing of supercoiled and linear isoforms
  • Detects impurities down to 25 pg/µL
  • Sample input size range 2-13kb
  • 21 CFR Part 11 capable
Click to copy promo code to clipboard.
img-icon-10-off-white-yellow.svg

SAVE 10% on your first Revvity.com order. Use promo code below.

HELLO10

Terms and conditions apply.

Product Variant
Unit Size: 480 samples
Part #:
CLS160450
List Price
USD 3,362.00
Your online price:
For research use only. Not for use in diagnostic procedures.
Total list price:
USD 3,362.00
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Overview

Streamline your pDNA workflow.

The LabChip™ Plasmid DNA assay is fully automated on both the LabChip GX Touch™ nucleic acid analyzer and the LabChip GXII Touch characterization system. It is designed to be used with the Plasmid DNA chip.

Compared to traditional methods such as slab gel electrophoresis, HPLC, or capillary electrophoresis, this innovative solution offers faster run times, simplified instrument and chip preparation, reliable results, and minimized sample handling.

Additional product information

Tailored to Your Workflow

pDNA typically exists in one of three isoforms: supercoiled, linear, or open circular. The preferred isoform varies based on its intended application. The electropherogram (Figure 1) shows the separation of the supercoiled, linear, and open circular pDNA. The LabChip pDNA Assay provides a complete solution for your plasmid analysis with clear resolved isoforms and impurity detection down to 25pg/uL.

pDNA-mixed-isoforms-sample-separation


Figure 1. Overlay electropherograms of 2.7, 4.4, 6.7 and 12.9 kb plasmid DNA mixed isoforms sample separation showing the separation of supercoiled (sc), linear (l), and open circular (OC) pDNA at 500 pg/µL

Features:

  • Flexible Sample Throughput 
    Capable of running 24 or 48 samples at once.
  • Small Sample Volumes
    Only 1-2 μL of undiluted sample volume is required for 384 and 96 well plates.
  • Simple Workflow
    No incubation time or filtration steps required.
  • Fast Analysis Time
    Achieve purity and sizing results of your pDNA isoforms in under 2 minutes per sample.
  • Scalable for your Processing Needs
    Process up to 480 samples with a single kit, supported by six-month reagent stability for consistent performance.
  • Walk-away Analysis
    Both the LabChip GX/GXII Touch systems enable walkway analysis with day-long or over-night runs possible.

Specifications

Shipping Conditions
Dual Temperature
Unit Size
480 samples

Resources

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Product Note Icon
Product Note
Automated DNA sample analysis.

Learn what fast and easy DNA analysis assays are available for the LabChip™ GX Touch Nucleic Acid Analyzer.

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Flyer
LabChip Windows 11

Learn how you can upgrade your LabChip GXII Touch or LabChip GX Touch system to Windows 11 to boost your productivity and enhance...

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Technical Note
Plasmid DNA characterization in less than 2 minutes per sample

Streamline your pDNA workflow.

In the fast-paced world of biotechnology, efficient and reliable plasmid DNA (pDNA) characterization...

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